Haptoglobin Phenotypes Are Associated with the Postload Glucose and Insulin Levels in Pediatric Obesity.
Roberta RicottiMarilisa De FeudisCaterina PeriMarco CorazzariGiulia GenoniMara GiordanoValentina MancioppiEmanuela AgostiSimonetta BelloneFlavia ProdamPublished in: International journal of endocrinology (2020)
To our knowledge, this is the first study on Hp phenotypes conducted in a pediatric population with obesity. We showed that the presence of Hp2 allele is associated with a worse response of glucose load in terms of both glucose and insulin levels. Thus, the Hp2-2 phenotype could predispose in pediatrics, at the same degree of obesity, to a worse glycemic and insulinemic compensation.