Randomized Clinical Trial of Intravenous Acetaminophen as an Analgesic Adjunct for Older Adults With Acute Severe Pain.

Andrew K ChangPolly E BijurAshar AtaCaron CampbellScott PearlmanDeborah WhiteAndrew ChertoffAndrew RestivoE John Gallagher

Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2018)

In this randomized clinical trial, the addition of IV acetaminophen to IV hydromorphone as an adjunctive analgesic for acute, severe, pain in older adults provided neither clinically nor statistically superior pain relief when compared to hydromorphone alone within the first hour of treatment.

Keyphrases

neuropathic pain
chronic pain
drug induced
liver injury
pain management
liver failure
physical activity
respiratory failure
spinal cord
early onset
blood pressure
spinal cord injury
clinical trial
double blind
high dose
hepatitis b virus
intensive care unit
replacement therapy