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Beyond blood biomarkers: the role of SelectMDX in clinically significant prostate cancer identification.

Matteo FerroMartina MaggiGiuseppe LucarelliUgo Giovanni FalagarioFrancesco Del GiudiceFelice CrocettoBiagio BaroneEvelina La CivitaFrancesco LasorsaAntonio BresciaMichele CatellaniGian Maria BusettoOctavian Sabin TataruDaniela Terracciano
Published in: Expert review of molecular diagnostics (2023)
Several PCa biomarkers have been developed either alone or in combination with clinical variables to improve csPCa detection. SelectMDX® score includes genomic markers, age, PSA, prostate volume, and digital rectal examination. Several studies showed consistence in the ability to improve detection of csPCa, avoidance of unnecessary prostate biopsies, helpful in decision making for clinical benefit of PCa patients with future well designed, and impactful studies.
Keyphrases
  • prostate cancer
  • radical prostatectomy
  • decision making
  • real time pcr
  • label free
  • benign prostatic hyperplasia
  • gene expression
  • current status
  • copy number
  • sensitive detection