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Anatomical and functional changes in neovascular AMD in remission: comparison of fibrocellular and fibrovascular phenotypes.

Lea QuerquesMariacristina ParravanoEnrico BorrelliAdele ChiaravallotiMassimiliano TedeschiRiccardo SacconiIlaria ZucchiattiFrancesco Maria BandelloFrancesca Amoroso
Published in: The British journal of ophthalmology (2019)
Neovascular AMD eyes in remission and with evidence of fibrocellular scar are characterised by RPE atrophy and reduced perfusion, which are associated with a higher degree of functional impairment. These findings suggest that maturation of vessels in fibrosis might be a better target in neovascular AMD treatments rather than their abolishment.
Keyphrases
  • age related macular degeneration
  • disease activity
  • ulcerative colitis
  • optical coherence tomography
  • rheumatoid arthritis
  • magnetic resonance imaging
  • computed tomography
  • vascular endothelial growth factor