Clinical correlates of early onset antipsychotic treatment resistance.
Daniela Fonseca de FreitasDeborah AgbedjroGiouliana Kadra-ScalzoEmma FrancisIsobel RidlerMegan PritchardHitesh ShettyAviv SegevCecilia CasettaSophie E SmartAnna MorrisJohnny DownsSøren Rahn ChristensenNikolaj BakBruce J KinonDaniel StahlRichard D HayesJames Hunter MacCabePublished in: Journal of psychopharmacology (Oxford, England) (2022)
Our findings do not support a clear separation between early and late TRS but rather a continuum of the length of treatment before TRS onset. Having mild to very severe problems with positive symptoms at treatment start predicts earlier onset of TRS.