Laser-responsive sequential delivery of multiple antimicrobials using nanocomposite hydrogels.
Meera PatelAlexander Lucien CorbettAarushi VardhanKeuna JeonNesha May O AndoyRuby May Arana SullanPublished in: Biomaterials science (2023)
Precise control of antimicrobial delivery can prevent the adverse effects of antibiotics. By exploiting the photothermal activity of polydopamine nanoparticles along with the distinct transition temperatures of liposomes, a near-infrared (NIR) laser can be used to control the sequential delivery of an antibiotic and its adjuvant from a nanocomposite hydrogel-preventing bacterial growth.
Keyphrases
- drug delivery
- drug release
- cancer therapy
- photodynamic therapy
- reduced graphene oxide
- hyaluronic acid
- quantum dots
- staphylococcus aureus
- early stage
- high speed
- wound healing
- emergency department
- gold nanoparticles
- visible light
- high resolution
- extracellular matrix
- magnetic nanoparticles
- simultaneous determination
- walled carbon nanotubes