Efficacy of naloxegol on symptoms and quality of life related to opioid-induced constipation in patients with cancer: a 3-month follow-up analysis.

Manuel CoboCarmen Beato ZambranoLuis Cabezón GutiérrezRodolfo Chicas SettMaría Isabel Blancas López-BarajasFrancisco García NavalónJosé Luis Fírvida PérezGala Serrano BermúdezPilar Togores TorresIgnacio Delgado MingoranceAlexandra Giraldo MarínAnna Librán OriolAlfredo Paredes LarioPedro Sánchez MauriñoOliver Higuera GómezDiana Moreno MuñozAntonio Javier Jiménez LópezIbone Huerta GonzálezAlmudena Sanz YagüeBegoña Soler-López

Published in: BMJ supportive & palliative care (2020)

Clinically relevant improvements in OIC-related quality of life, number of bowel movements and constipation-related symptoms were recorded as early as after 15 days of treatment with naloxegol in patients with cancer and OIC, with a good safety profile.

Keyphrases

chronic pain
drug induced
physical activity
combination therapy
replacement therapy
stress induced