Expression patterns of CD28 and CTLA-4 in early, chronic, and untreated rheumatoid arthritis.
Mariel García-ChagollánIris Yolanda Ledezma-LozanoJorge Hernández-BelloPedro Ernesto Sánchez-HernándezSergio Ramón Gutiérrez-UreñaJosé Francisco Munoz-VallePublished in: Journal of clinical laboratory analysis (2020)
In RA, the percentage of CD8 + CD28+ T cells decreases and expresses fewer membrane CD28 than CS. sCD28 levels are lower in chronic RA and are associated negatively with anti-CCP levels. sCTLA 4 levels are lower in early RA patients than in untreated RA patients.