Time course of arsenic species in red blood cells of acute promyelocytic leukemia (APL) patients treated with single agent arsenic trioxide.

Meihua GuoBin WangShuchuan LiuWenjing WangChunlu GaoShuang HuShengjin FanXin HaiJin Zhou

Published in: Expert review of clinical pharmacology (2019)

Time course of arsenic species reveal kinetic characteristic of ATO metabolites in RBCs. Arsenic species accumulated with administration frequency. Arsenic species in RBCs were remarkably different from those in plasma. Time course of arsenic species in RBCs is important in ATO clinical application.

Keyphrases

drinking water
heavy metals
red blood cell
genetic diversity
ms ms
acute myeloid leukemia
genome wide
risk assessment
dna methylation
drug induced