Neutrophil extracellular trap-associated carbamylation and histones trigger osteoclast formation in rheumatoid arthritis.
Liam J O'NeilChristopher B OliveiraXinghao WangMario NavarreteAna Barrera-VargasJavier Merayo-ChalicoRwan AljahdaliEduardo Aguirre-AguilarPhilip M CarlucciMariana J KaplanCarmelo Carmona-RiveraPublished in: Annals of the rheumatic diseases (2023)
Our results suggest that NETs have a direct role in RA-associated bone erosion by promoting osteoclast formation.