Prenatal Diagnostic Value of Chromosomal Microarray in Fetuses with Nuchal Translucency Greater than 2.5 mm.

Zhu ZhangTing HuJiamin WangQinqin LiHe Wang Shanling Liu

Published in: BioMed research international (2019)

It is rational to use a diagnostic strategy in which CMA is preceded by a less-expensive, rapid method, namely, QF-PCR, to detect common aneuploidies. CMA allows for the detection of a number of pathogenic chromosomal aberrations in fetuses with an NT ≥ 2.5 mm.

Keyphrases

copy number
loop mediated isothermal amplification
gestational age
real time pcr
pregnant women
genome wide
sensitive detection
dna methylation
label free