Glucose-6-phosphate dehydrogenase deficiency as a cause for nonimmune hydrops fetalis and severe fetal anemia: A systematic review.
Neel S IyerMatthew H MossayebiTracy J GaoLylach Haizler-CohenDaniele Di MascioRodney A McLarenHuda B Al-KouatlyPublished in: Molecular genetics & genomic medicine (2024)
Six cases of NIHF/severe fetal anemia were associated with G6PD deficiency. While G6PD deficiency is an X-linked recessive condition, female fetuses can be affected. Fetal G6PD deficiency testing can be considered if parental history indicates, particularly if the standard workup for NIHF is negative.