DNA methylation is associated with lung function in never smokers.

Maaike M De VriesIvana NedeljkovicDiana A van der PlaatAlexandra ZhernakovaLies LahousseGuy G Brussellenull nullNajaf AminCornelia M van DuijnJudith M VonkH Marike Boezen

Published in: Respiratory research (2019)

With the identification of 35 CpG-sites that are unique for never smokers, our study shows that DNA methylation is also associated with FEV1/FVC in subjects that never smoked and therefore not merely related to smoking.

Keyphrases

dna methylation
lung function
smoking cessation
genome wide
gene expression
chronic obstructive pulmonary disease
cystic fibrosis
air pollution
copy number