Validation and benchmarking of targeted panel sequencing for cancer genomic profiling.

Duo WangSizhen WangYuanfeng ZhangXiaolei ChengXin HuangYanxi HanZhaohui ChenCong LiuJinming LiRui Zhang

Published in: American journal of clinical pathology (2023)

This study presents a detailed validation framework and empirical recommendations for large panel validation and elucidates the sources of discordant alteration calls by comparing with "gold standard measures."

Keyphrases

single cell
papillary thyroid
gene expression
squamous cell carcinoma
cancer therapy
clinical practice
silver nanoparticles