Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection.

Erica DaoGabriella GohlaPhillip WilliamsPeter LovricsFares BadrQiyin FangThomas J FarrellMichael J Farquharson

Published in: Journal of biomedical optics (2023)

The combined TRF-DR system showed greater tissue classification capability than either technique alone. Further work studying more fibroglandular tissue and tissue of mixed composition would develop this system for intraoperative use for tumor margin detection.

Keyphrases

machine learning
high resolution
patients undergoing
low grade
high speed
high grade
quantum dots
sensitive detection