Differences in the genetic backgrounds of patients with alcoholic liver disease and non-alcoholic fatty liver disease.

Kuniko YamamotoTomomi Kogiso Makiko TaniaiEtsuko HashimotoKatsutoshi Tokushige

Published in: JGH open : an open access journal of gastroenterology and hepatology (2018)

SNPs in genes related to ethanol and lipid metabolism clearly differed between patients with ALD and NAFLD. KCNQ1 might affect the progression and hepatocarcinogenesis in both ALD and NAFLD.

Keyphrases

genome wide
dna methylation
copy number
liver injury
drug induced
genome wide identification
bioinformatics analysis