Comparison of medication adherence measures derived from linked administrative data and associations with mortality using restricted cubic splines in heart failure patients.

Xiwen QinJoseph HungMatthew W KnuimanTom G BriffaTiew-Hwa Katherine TengFrank M Sanfilippo

Published in: Pharmacoepidemiology and drug safety (2020)

Proportion of days covered calculated from administrative drug data provides a more conservative estimate of adherence than MPR or MPRm and was the most consistent predictor of subsequent mortality in an HF cohort using RCS analysis.

Keyphrases

cardiovascular events
electronic health record
big data
risk factors
ejection fraction
data analysis
coronary artery disease
heart failure
machine learning
artificial intelligence
deep learning