Factors predicting mortality in hospitalised HIV-negative children with lower-chest-wall indrawing pneumonia and implications for management.
Katherine E GallagherJuliet O AworiMaria Deloria KnollJulia RhodesMelissa M HigdonLaura L HammittChristine ProsperiHenry C BaggettW Abdullah BrooksNicholas FancourtDaniel R FeikinStephen R C HowieKaren L KotloffMilagritos D TapiaOrin S LevineShabir A MadhiDavid R MurdochKatherine L O'BrienDonald M TheaVicky L BaillieBernard E EbrukeAlice KamauDavid P MooreLawrence MwananyandaEmmanuel O OlutundePhil SeidenbergSamba O SowSomsak ThamthitiwatJ Anthony G Scottnull nullPublished in: PloS one (2024)
Although it focuses on treatment failure in hospital, this study supports the proposal for better risk stratification of children with LCWI pneumonia. Those who have hypoxaemia, any malnutrition or those who were born to HIV positive mothers, experience poorer outcomes than other children with LCWI pneumonia. Consistent identification of these risk factors should be prioritised and children with at least one of these risk factors should not be managed in the community.