GFI1 Cooperates with IKZF1/IKAROS to Activate Gene Expression in T-cell Acute Lymphoblastic Leukemia.

Wenxiang SunJingtao GuoDavid McClellanAlexandra PoeschlaDiana BareyanMattie J CaseyBradley R CairnsDean TantinMichael E Engel

Published in: Molecular cancer research : MCR (2022)

Combinatorial diversity and cooperation between DNA binding proteins and complexes assembled by them can direct context-dependent transcriptional outputs to control cell fate and may offer new insights for therapeutic targeting in cancer.

Keyphrases

acute lymphoblastic leukemia
gene expression
cell fate
papillary thyroid
allogeneic hematopoietic stem cell transplantation
dna methylation
squamous cell
circulating tumor
cell free
single molecule
cancer therapy
lymph node metastasis
childhood cancer
young adults
nucleic acid
acute myeloid leukemia