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Mutations in complement C3 from aHUS patients.
Gregers Rom Andersen
Published in:
Blood (2015)
In this issue of Blood, Schramm et al demonstrate that the majority of mutations in complement C3 identified in atypical hemolytic uremic syndrome (aHUS) patients cause dysregulation in the alternative pathway of complement.
Keyphrases
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end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
patient reported outcomes
patient reported