Pulmonary hemodynamics and effects of phosphodiesterase type 5 inhibition in heart failure: a meta-analysis of randomized trials.

In-Chang HwangYong Jin KimJun-Bean ParkYeonyee E YoonSeung-Pyo LeeHyung-Kwan KimGoo-Yeong ChoDae-Won Sohn

Published in: BMC cardiovascular disorders (2017)

PDE5i improved pulmonary hemodynamics and exercise capacity in patients with HFrEF, but not in HFpEF. The relationship between the benefits by PDE5i with the baseline PAP and the changes in PAP indicates the therapeutic potential of PDE5i in HF according to pulmonary hemodynamics.

Keyphrases

pulmonary hypertension
heart failure
acute heart failure
physical activity
high intensity
left ventricular
atrial fibrillation
body composition