Clinical Utility of Stepwise Bronchoalveolar Lavage Fluid Analysis in Diagnosing and Managing Lung Infiltrates in Leukemia/Lymphoma Patients With Febrile Neutropenia.
Jayashree ThoratSurabhi BhatManju SengarAkshay D BahetiSweta BothraMaheema BhaskarSandeep Prakashnarain TandonSanjay K BiswasGaurav V SalunkeGeorge KarimundackalVirendra Kumar TiwariConjeevaram S PrameshNeha SharmaVenkatesh KapuThomas EipeBhausaheb Pandurang BagalLingaraj NayakAvinash BondaAmit JanuAlok ShettyHashmukh JainPublished in: JCO global oncology (2024)
Our study demonstrates that a two-step BAL fluid analysis is safe and clinically beneficial to establish an accurate microbiological diagnosis. Given the crucial impact of diagnostic delays on mortality in hematologic malignancy patients with FN, early BAL studies should be performed to enable prompt and specific diagnosis, allowing for appropriate treatment modifications.