KS0365, a novel activator of the transient receptor potential vanilloid 3 (TRPV3) channel, accelerates keratinocyte migration.
Marion MaierStefan OlthoffKerstin HillCarolin ZoselThomas MagauerLukas Anton WeinMichael SchaeferPublished in: British journal of pharmacology (2022)
The selective TRPV3 activator KS0365 triggers increases in [Ca<sup>2+</sup> ]<sub>i</sub> with most prominent signals in the leading edge and accelerates migration of keratinocytes. TRPV3 activators may promote re-epithelialization upon skin wounding.