Comparison of GeneXpert MRSA/SA ETA assay with semi-quantitative and quantitative cultures and nuc gene-based qPCR for detection of Staphylococcus aureus in endotracheal aspirate samples.
Jasmine CoppensLiesbet Van HeirstraetenAlexey RuzinLi YuLeen TimbermontChristine LammensVeerle MatheeussenMichael McCarthyPhilippe JorensMargareta IevenSamir Kumar-SinghHerman GoossensSurbhi Malhotra-KumarPublished in: Antimicrobial resistance and infection control (2019)
This first evaluation of the GeneXpert MRSA/SA ETA assay with ETA samples found it to be highly sensitive, specific, user-friendly (hands-on time ~ 5 min.), and rapid (~ 66 min. assay time). Where this equipment is not available, we recommend implementing more sensitive culture-based methods for improved S. aureus detection in ETA samples.