Analysis of glaucoma genes in Finnish patients with juvenile open-angle glaucoma.

Perttu J LiuskaAbdessallam TadjiPauliina E RepoJuho HiltunenMichael Paul BacklundReetta-Stiina JärvinenEeva OjanenAnna Majander Tero Tapani Kivelä Mika Harju Joni Antero Turunen

Published in: Acta ophthalmologica (2023)

The frequency of pathogenic variants in previously known glaucoma-associated genes is low in Finnish patients with JOAG. Because of the distinct genetic background of Finns, it might be possible to identify novel glaucoma genes through our JOAG series in the future.

Keyphrases

genome wide
optic nerve
bioinformatics analysis
copy number
genome wide identification
dna methylation
cataract surgery
genome wide analysis
gene expression
current status
optical coherence tomography