Analysis of the variable factors affecting changes in the blood concentration of cyclosporine before and after transfusion of red blood cell concentrate.
Masashi UchidaNatsumi HanadaShingo YamazakiHirokazu TakatsukaChiaki ImaiAkari UtsumiYuki ShikoYohei KawasakiTakaaki SuzukiItsuko IshiiPublished in: Journal of pharmaceutical health care and sciences (2022)
A change in the blood concentration/dose ratio of CyA was found to be associated with a change in the HCT, concomitant medication that could elevate CyA concentration after RCC transfusion, and ALP levels. If the HCT level rises significantly after RCC transfusion, clinicians and pharmacists should pay attention to changes in the blood CyA concentration.