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Inflammation Is More Sensitive than Cell Proliferation in Response to Rapamycin Treatment in Polycystic Kidney Disease.

Ming YangJiayi LvChanjuan GongCheng XueLili FuShunjie ChenChanglin Mei
Published in: Kidney & blood pressure research (2024)
Low dose of rapamycin could inhibit inflammation and protect renal function in PKD. Inflammation is more sensitive than cell proliferation in response to rapamycin treatment in PKD.
Keyphrases
  • polycystic kidney disease
  • cell proliferation
  • oxidative stress
  • low dose
  • cell cycle
  • high dose
  • combination therapy
  • pi k akt
  • replacement therapy