Urinary volatile organic compound markers and colorectal anastomotic leakage.

Victor D PlatB T BootsmaM NealK NielsenD J A SonneveldJ J C TersteegR M P H CrollaD A van DamH A CenseH B A C StockmannJ A CovingtonT G J de MeijJ B TuynmanN K H de BoerF Daams

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2019)

Analysis by FAIMS allowed for discrimination between urinary VOC profiles of patients with a confirmed anastomotic leak and control patients following colorectal surgery. A superior accuracy compared to CRP and apparently high specificity was observed, underlining the potential as a non-invasive biomarker for the detection of colorectal anastomotic leakage.

Keyphrases

rectal cancer
end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
gas chromatography
water soluble