Apolipoprotein E moderates the association between Non- APOE Polygenic Risk Score for Alzheimer's Disease and Aging on Preclinical Cognitive Function.
Yuexuan XuZhongxuan SunErin JonaitisYuetiva K DemingQiongshi LuSterling C JohnsonCorinne D EngelmanPublished in: medRxiv : the preprint server for health sciences (2023)
ε4 carriers with high PRS are the most vulnerable to the harmful effects caused by genetic burden.