Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats.

Hidetsugu MaekawaYoshiteru TadaKenji YagiTakeshi MiyamotoKeiko T KitazatoMasaaki KoraiJunichiro SatomiTomoki HashimotoShinji Nagahiro

Published in: Journal of neuroinflammation (2017)

Our observation that bazedoxifene decreased the incidence of aneurysmal rupture in ovariectomized rats warrants further studies to validate this response in humans.

Keyphrases

estrogen receptor
bone loss
coronary artery
subarachnoid hemorrhage
case control
cerebral blood flow