Is there no need to discuss adjuvant chemotherapy in stage II colon cancer patients with high tumor budding and lymphovascular invasion?
Serkan ZengerBulent GurbuzUgur CanErgin ErginozIbrahim Halil OzataSerpil Postgil YilmazOrhun Cig TaskinOnder PekerN Volkan AdsayEmre BalikDursun BugraPublished in: Langenbeck's archives of surgery (2023)
In patients with T3/4aN0 colon cancer, high tumor budding negatively affects long-term oncological outcomes. These findings strongly suggest that adjuvant chemotherapy be considered for the patients with Bd3 and LVI together.