NSUN2 promotes colorectal cancer progression by enhancing SKIL mRNA stabilization.
Shaomin ZouYizhi HuangZiqing YangJieping ZhangManqi MengYijing ZhangJunyan FengRui SunWeiyao LiWencong WangJesús García-Foncillas LópezLekun FangPublished in: Clinical and translational medicine (2024)
Our findings highlight the importance of NSUN2 in the initiation and progression of CRC via m5C-YBX1-dependent stabilization of the SKIL transcript, providing a promising targeted therapeutic strategy for CRC.
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