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C3 glomerulopathy associated with monoclonal gammopathy: impact of chronic histologic lesions and beneficial effects of clone-targeted therapies.

Fernando Caravaca-FontánLaura LucientesNúria SerraTeresa CaveroRaquel RodadoNatalia RamosFayna GonzalezAmir ShabakaVirginia CabelloAna HuertaSaúl Pampa-SaicoEduardo GutiérrezLuis F QuintanaMaria Esperanza López-RubioJuliana DraibeJuana Alonso TitosGema Fernández-JuárezElena Goicoechea de JorgeManuel Praga
Published in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2021)
The C3G histologic index can be used in patients with C3G-MIg to predict kidney prognosis, with higher chronicity scores being associated with worse outcomes. Clone-targeted therapies and the development of hematological response, are associated with better kidney prognosis.
Keyphrases
  • adipose tissue
  • drug induced
  • weight loss