We admitted a 41-year-old man with a chief complaint of multiple nodules found in the scrotum, accompanied by itching discomfort, occasionally some nodules discharged white secretions. Physical examination revealed extensive nodules of scrotal skin, approximately 2.0 cm in diameter in the largest, grayish white, textured hard, no pain, no breakdown of skin. Due to the wide distribution of scrotal nodules in this patient, there was a large deletion in the scrotal skin after intraoperative removal of all nodules; the skin was submitted to V and Z-sutures, and the scrotum was finally successfully reconstructed.