Alcohol (70%) versus alcoholic chlorhexidine solution (0.5%) in skin antisepsis for neuraxial blocks: a randomized clinical trial.

Luiz Carlos Souza TostesAna Beatriz Alkmim Teixeira LoyolaAdilson DE Oliveira FragaLetÍcia Azevedo GazziLuiz Francisley DE PaivaYara JulianoDaniela Francescato Veiga

Published in: Revista do Colegio Brasileiro de Cirurgioes (2021)

70% alcohol was more effective in reducing the number of CFU/cm² after two minutes, and there was no difference between the two groups regarding skin colonization at the end of the procedure. These results suggest that 70% alcohol may be an option for skin antisepsis before neuraxial blocks. Trial registration: ClinicalTrials.gov, NCT02833376.

Keyphrases

soft tissue
wound healing
alcohol consumption
minimally invasive
phase iii
phase ii
liver injury
open label
surgical site infection