Adaptive Randomization Method to Prevent Extreme Instances of Group Size and Covariate Imbalance in Stroke Trials.

Dominic Italiano Bruce C V CampbellMichael D HillHannah T Johns Leonid Churilov

Published in: Stroke (2024)

The proposed adaptive CSSize-MSB algorithm successfully controls for group size imbalance in hyperacute stroke trials under various settings, and its logic can be readily explained to clinicians using dynamic visualization.

Keyphrases

atrial fibrillation
machine learning
palliative care
climate change
deep learning
cerebral ischemia
neural network
blood brain barrier