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[Neopterin as a potential biomarker in neuropsychiatry].

Yu E ShilovI I Miroshnichenko
Published in: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2020)
The importance of finding predictors or biomarkers of neuropsychiatric pathology, as well as methods of its prevention, treatment and early diagnosis is beyond question. The level of neopterin in body fluids is one of the possible biomarkers. Increased levels of neopterin in biological fluids (e.g., serum, cerebrospinal fluid or urine) are closely associated with various diseases associated with cellular immune response. The data presented in the review indicate the relevance of the study of neopterin concentrations in body fluids in patients with mental illness for the development of diagnostic and prognostic tests or as a pharmacodynamic marker of drug action.
Keyphrases
  • mental illness
  • immune response
  • cerebrospinal fluid
  • mental health
  • electronic health record
  • dendritic cells
  • deep learning
  • data analysis
  • adverse drug