A National Cancer Database analysis of the patterns of care for meningeal melanocytoma.
Amanda C TepPatrick D KellyDaphne B ScarpelliBailey BergueShearwood McClelland IiiJerry J JaboinPublished in: Future oncology (London, England) (2021)
Aim: To evaluate demographics, treatment patterns, radiotherapy utilization and patient outcomes in meningeal melanocytomas. Materials & methods: The National Cancer Database was queried for meningeal melanocytomas diagnosed in 2002-2016. The effects of demographic, clinical and treatment variables were determined via Kaplan-Meier log-rank and Cox regression analyses. Results: The median and 5-year overall survival were 57.46 months and 48%, respectively. Patients earning ≥$48K showed improved survival (p = 0.0319). Radiotherapy and chemotherapy were utilized in 37.7 and 9% of patients, respectively. Conclusion: Income significantly affected survival. Surgery remains the mainstay approach. Radiotherapy was delivered in more than one-third of patients but did not impact survival. However, further analyses were limited by poor treatment modality information in the database.
Keyphrases
- end stage renal disease
- newly diagnosed
- ejection fraction
- chronic kidney disease
- early stage
- prognostic factors
- peritoneal dialysis
- radiation therapy
- locally advanced
- emergency department
- radiation induced
- palliative care
- mental health
- patient reported outcomes
- rectal cancer
- adverse drug
- electronic health record
- drug induced