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Plasma neurofilament light chain concentrations as a biomarker of clinical and radiologic outcomes in relapsing multiple sclerosis: Post hoc analysis of Phase 3 ozanimod trials.

Sarah HarrisGiancarlo ComiBruce A C CreeDouglas L ArnoldLawrence SteinmanJames K SheffieldHarry SouthworthLudwig KapposJeffrey A Cohennull null
Published in: European journal of neurology (2021)
pNfL was associated with clinical and radiologic measures of disease and treatment effects in RMS, supporting its use as a biomarker.
Keyphrases
  • multiple sclerosis
  • white matter
  • adipose tissue
  • rheumatoid arthritis
  • combination therapy
  • replacement therapy
  • weight loss