Impact of Focal White Matter Damage on Localized Subcortical Gray Matter Atrophy in Multiple Sclerosis: A 5-Year Study.
Tom A FuchsK CarolusRalph H B BenedictNiels P BergslandDeepa P RamasamyDejan JakimovskiBianca Weinstock-GuttmanAmy F KuceyeskiRobert ZivadinovMichael G DwyerPublished in: AJNR. American journal of neuroradiology (2018)
WM tract disruption accounts for a small percentage of atrophy in connected subcortical gray matter when controlling for overall disease burden and is not the primary driver in most cases.