The Role of Autotaxin and LPA Signaling in Embryonic Development, Pathophysiology and Cancer.
Christiana MagkriotiEleanna KaffeVassilis AidinisPublished in: International journal of molecular sciences (2023)
Autotaxin (ATX) or Ectonucleotide Pyrophosphatase/Phosphodiesterase 2 (ENPP2) is a secreted enzyme with lysophospholipase D activity, with its primary function being the extracellular hydrolysis of lysophosphatidylcholine (LPC) to lysophosphatidic acid (LPA), a bioactive lipid [...].