Effect of Enzyme-Inducing Antiseizure Medications on the Risk of Sub-Therapeutic Concentrations of Direct Oral Anticoagulants: A Retrospective Cohort Study.

Amichai PerlmanRachel GoldsteinLotan Choshen CohenBruria Hirsh-RaccahDavid HakimianIlan MatokYosef KalishDaniel E SingerMordechai Muszkat

Published in: CNS drugs (2021)

Concurrent EI-ASM and DOAC use presents a possible risk for DOAC concentrations below the expected range. The clinical significance of the interaction is currently unclear.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
locally advanced
squamous cell carcinoma
radiation therapy
rectal cancer