Promising aberrant DNA methylation marker to predict gastric cancer development in individuals with family history and long-term effects of H. pylori eradication on DNA methylation.

Hee Jin KimNa Young KimHyoung Woo KimJi Hyun ParkCheol Min ShinDong Ho Lee

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2020)

The methylation of MOS and CDH1 provided an association between aberrant DNA methylation and gastric carcinogenesis in FH of GC, a useful marker for GC risk in individuals with FH. Furthermore, CDH1 methylation decreased after Hp eradication.

Keyphrases

dna methylation
genome wide
gene expression
helicobacter pylori infection
copy number
quantum dots
gas chromatography
simultaneous determination
solid phase extraction