Cure With Interferon-Free Direct-Acting Antiviral Is Associated With Increased Survival in Patients With Hepatitis C Virus-Related Hepatocellular Carcinoma From Both East and West.
Hansen DangYee Hui YeoSatoshi YasudaChung-Feng HuangEtsuko IioCharles LandisDae Won JunMasaru EnomotoEiichi OgawaPei-Chien TsaiAn LeMatthew LiuMayumi MaedaBrian NguyenNathan RamrakhianiLinda HenryRamsey CheungAkihiro TamoriTakashi KumadaYasuhito TanakaMing-Lung YuHidenori ToyodaMindie H NguyenPublished in: Hepatology (Baltimore, Md.) (2020)
In this multinational consortium, patients with HCV-related HCC who obtained SVR achieved a 60%-70% improvement in 5-year survival (both all-cause and liver related) compared with patients untreated for HCV. Patients eligible for HCC therapy should also be considered for DAA therapy.