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Pupil size and pupillary light reflex in early infancy: heritability and link to genetic liability to schizophrenia.

Ana Maria PortugalMark J TaylorCharlotte ViktorssonPär NyströmDanyang LiKristiina TammimiesAngelica RonaldTerje Falck-Ytter
Published in: Journal of child psychology and psychiatry, and allied disciplines (2021)
This study shows that some pupil measures are highly heritable in early infancy, although substantially independent in their genetic etiologies, and associated with common genetic variants linked to schizophrenia. It illustrates how genetically informed studies of infants may help us understand early physiological responses associated with psychiatric disorders which emerge much later in life.
Keyphrases
  • bipolar disorder
  • genome wide
  • copy number
  • dna methylation