Identification and functional validation of rare coding variants in genes linked to monogenic obesity.
Çiğdem KöroğluMichael TraurigYunhua L MullerSamantha E DayPaolo PiaggiKim WiedrichLaura VazquezRobert L HansonCristopher V Van HoutAnna AlkelaiAlan R ShuldinerClifton BogardusLeslie J BaierPublished in: Obesity (Silver Spring, Md.) (2024)
In addition to MC4R, rare missense variants in KSR2 and NTRK2 may potentially explain the severe obesity observed for the carriers.