Prognostic benefit of comprehensive genomic profiling in clinical practice remains uncertain.

Published in: Cancer science (2023)

The overall survival of patients who received genomically matched therapy was not significantly longer than that of patients receiving treatment only other than genomically matched therapy in the breast invasive ductal carcinoma (A), colorectal adenocarcinoma (B), and pancreatic adenocarcinoma (C) cohorts.

Keyphrases

clinical practice
squamous cell carcinoma
gene expression
copy number
dna methylation
replacement therapy
combination therapy
radiation therapy
smoking cessation
genome wide
locally advanced