Placental endovascular extravillous trophoblasts (enEVTs) educate maternal T-cell differentiation along the maternal-placental circulation.

Yeling MaQian YangMengjie FanLanmei ZhangYan GuWentong JiaZhilang LiFeiyang WangYu-Xia LiJian WangRong LiXuan Shao Yan-Ling Wang

Published in: Cell proliferation (2020)

Our findings demonstrate a unique immune-regulatory characteristic of placental enEVTs to develop immune tolerance along the placental-maternal circulation. New insights into the pathogenesis of RSA are also suggested.

Keyphrases

birth weight
pregnancy outcomes
transcription factor
weight gain
gestational age
body mass index
weight loss
preterm birth