Efficacy of PD-1/PD-L1 inhibitors in patients with non-small cell lung cancer and brain metastases: A real-world retrospective study in China.
Jia-Min ShengHui LiXiaoqing YuSizhe YuKai-Yan ChenGuoqiang PanMing-Ying XieNa LiZi-Chao ZhouYun FanPublished in: Thoracic cancer (2021)
In NSCLC-BMs patients lacking driver genes, ICIs exhibited an effective drug regime. A combination of ICIs with concurrent radiotherapy showed a better intracranial response, whereas ICIs plus chemotherapy were associated with superior OS.
Keyphrases
- brain metastases
- small cell lung cancer
- locally advanced
- end stage renal disease
- chronic kidney disease
- ejection fraction
- early stage
- radiation therapy
- peritoneal dialysis
- prognostic factors
- squamous cell carcinoma
- genome wide
- emergency department
- rectal cancer
- dna methylation
- transcription factor
- optical coherence tomography
- electronic health record
- genome wide identification