Lipopolysaccharides affect compressed periodontal ligament cells via Eph-ephrin signaling.

Minjie LiZhongyuan TangCheng Fei ZhangLijian JinKoichi MatsuoYanqi Yang

Published in: Oral diseases (2021)

Simultaneous LPS and CF stimulation critically enhances osteoclastogenesis in PDLCs through the suppression of EphB4 and the induction of ephrinA2 signaling. Sequential LPS and CF exposure partially abolishes the osteolytic effects of simultaneous stimulation.

Keyphrases

cystic fibrosis
inflammatory response
induced apoptosis
anti inflammatory
cell cycle arrest
lps induced
endoplasmic reticulum stress
signaling pathway
cell death
cell proliferation
pi k akt